Biocatalysis: Accelerating Chemical Development and Minimising Cost for Fine Chemical / API Manufacture and Metabolite Synthesis

There is a growing acceptance and use of biocatalysis in industry, not only as an alternative to conventional chemistry optimisation and scale‑up but as the preferential technique. The authors evaluate the developments of the last 10 years that have predicated this systemic change in approach.
In addition, recent innovations are continuing to drive forward biocatalysis as a maturing technology in the delivery of chiral intermediates, fine chemicals and APIs.