API, Chemical Development & Analytical Services / Efficient kinetic bioresolution of 2-nitrocyclohexanol

Technical Publication

Efficient kinetic bioresolution of 2-nitrocyclohexanol

The kinetic bioresolution of 2-nitrocyclohexanol 1 was investigated by screening a range of hydrolases both for enantioselective transesterification and for enantioselective hydrolysis of the corresponding acetate.
By appropriate choice of biocatalyst and conditions, both enantiomers of cis and trans 2-nitrocyclohexanol 1 can be accessed in enantiopure form.

View Resource

Almac API, Chemical Development, Analytical & Solid State Services

Almac Sciences provides integrated services from development to commercial scale of advanced intermediates and Active Pharmaceutical Ingredients (API).

We provide a range of services for small molecules (including highly potent) and peptides. We have a proven track record of saving time and cost through the integration of our services and application of innovative biocatalysis and technology solutions.

Learn More

We offer a full suite of analytical testing for a range of different product types including small molecules, peptides, biologics, conjugates, potent and controlled substances.

Our vast pool of scientific knowledge can help to overcome the analytical challenges that typically arise during drug development.

Learn More

You may also be interested in

Article

Development and Scale-Up of 7‑COOH CBD Synthesis, a Key Cannabinoid Metabolite

Article

Preparative Chromatography of Peptides and Other Large Molecules

Stay up-to-date with the latest from Almac

Join our mailing list

This website uses cookies. By continuing to browse the site, you are agreeing to our use of cookies

Download here instantly

Development and Scale-Up of 7‑COOH CBD Synthesis, a Key Cannabinoid Metabolite

Preparative Chromatography of Peptides and Other Large Molecules