API, Chemical Development & Analytical Services / Highly stereoselective biocatalytic reduction of alpha-halo ketones

Technical Publication

Highly stereoselective biocatalytic reduction of alpha-halo ketones

The use of recombinant carbonyl reductase biocatalysts for the reduction of alpha-halo ketone intermediates to their corresponding alpha-halo alcohols has been investigated. The alpha-halo alcohol is obtained in good yield from the corresponding ketone in a tereoselective manner.

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